Honors Theses

Date of Award

Spring 4-25-2022

Document Type

Undergraduate Thesis

Department

Biomolecular Sciences

First Advisor

Courtney Roper

Second Advisor

Jason Ritchie

Third Advisor

James Stewart

Relational Format

Dissertation/Thesis

Abstract

Fine particulate matter (PM2.5), the solid and liquid portion of air pollution under 2.5 microns in diameter, has been shown to cause numerous negative effects on the body. These inhalable particles are often researched for their effects on the respiratory system in outdoor settings, however systemic health impacts have been observed following inhalation of PM2.5 . Additionally, exposures to PM2.5 can occur in occupational settings but are less frequently studied compared to outdoors. This literature review seeks to identify studies that determined associations between inhaled PM2.5 and the resulting cardiovascular effects in occupational settings. We conducted a search of literature studying PM2.5 exposures and cardiovascular outcomes. We analyzed 31 articles pertaining to key cardiovascular effects of PM2.5 exposure in occupational settings, finding associations in 93.5% of cases. Because limited literature focuses on cardiovascular endpoints of PM2.5 specifically in occupational settings, it is important that additional research is conducted in order to more fully comprehend the direct effects that PM2.5 has on the cardiovascular system and other related cardiovascular risk factors.

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