Honors Theses

Date of Award

Spring 5-14-2023

Document Type

Undergraduate Thesis


Communication Sciences and Disorders

First Advisor

Toshikazu Ikuta

Second Advisor

Ryan Fortenberry

Third Advisor

Ikhlas Khan

Relational Format



A systematic review was conducted to show that BTX (Botulinum Toxin) is the most effective treatment for Abductor Spasmodic Dysphonia (ABSD). There were a total of 117 records screened for inclusion in this review. After the initial screening, there were seven successive rounds of screening for eligibility. This process produced a total of three eligible records that met the following conditions: patients presented with spastic abduction, electromyography BTX type A injection into the posterior cricoarytenoid muscle, and measurement of results with acoustic dimensions. After surveying all eligible studies, it was concluded that BTX is an effective treatment for ABSD. Every included study reported all patients with improvement after treatment, however, there was a considerable number of patients who experienced adverse effects. After the initial evaluation of BTX treatment, some patients required additional injections of BTX and/or surgery to maintain results. The use of this review should be used to catapult investigation into long term treatments for ABSD as well as the elimination of adverse effects

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Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Available for download on Monday, May 13, 2024