Honors Theses

Date of Award


Document Type

Undergraduate Thesis


Communication Sciences and Disorders

First Advisor

Toshikazu Ikuta

Relational Format



This thesis is a study of rsfMRI imaging in order to examine coactivation patters of the piriform cortex between healthy subjects and people with schizophrenia. As part of the olfactory system, the piriform cortex is an integral part of the smell sensation. Our studies showed that coactivation among the piriform cortex and other sensory brain regions differ in people with schizophrenia compared to healthy subjects. People with schizophrenia exhibit patterns of less coactivation among their sensory brain regions compared to control subjects, specifically the intracalcarine cortex, the right planum temporale, and the left occipital lobe. The purpose of this study is to gain a better understanding of schizophrenia functionality. Further studies of these results could be used to create novel therapies or identify new markers for schizophrenia.

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