Electronic Theses and Dissertations

Date of Award

2015

Document Type

Dissertation

Degree Name

M.S. in Health Promotion

Department

Health, Exercise Science, and Recreation Management

First Advisor

Paul D. Loprinzi

Second Advisor

Teresa Carithers

Third Advisor

Martha Bass

Relational Format

dissertation/thesis

Abstract

Background: little research has been conducted to describe the relationship between kidney stones and risk of cardiovascular disease and stroke in individuals of different race ethnicities. Purpose: the purpose of this study was to compare the prevalence of co-morbidities and to investigate whether there was a statistically significant association between kidney stone formers and increased odds of cardiovascular disease and stroke in race-ethnicity groups. Methods: data from the 2007-2012 cycles of the national health and nutrition examination survey (Nhanes) were used. Survey and biological data used included kidney stone cases, hypertension, obesity, diabetes, chronic kidney disease, cardiovascular disease and stroke. Covariates in the analytic models included ratio of family income to poverty, age, gender, education, diet, smoking and tobacco use, poverty level, physical activity, and alcohol use. Results: after adjusting for confounders, kidney stone participants had increased odds of obesity, hypertension, diabetes, cardiovascular disease, and stroke. Non-Hispanic black kidney stone formers, compared to other ethnic groups, had the highest prevalence of obesity (65.6%), hypertension (67.6%), diabetes (37.8%), and stroke (6.1%). However, Mexican American kidney stone formers had the highest prevalence of elevated cholesterol (38.2%), with non-Hispanic white kidney stone formers having the highest prevalence of cardiovascular disease (7.1%). Conclusion: we observed a relatively strong association between kidney stones and various morbidities, with these observations not appearing to be moderated by race-ethnicity. However, when utilizing the pooled cohort equations to predict 10-yr risk of a future ASCVD event, kidney stones was only associated with future risk among non-Hispanic black kidney stone formers

Included in

Epidemiology Commons

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