Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants.

Authors

• Farida Larit, University of Mississippi
• Khaled M. Elokely, Tanta University
• Narayan D. Chaurasiya, University of Mississippi
• Samira Benyahia, Université Badji Mokhtar
• Manal A. Nael, Tanta University
• Francisco León, University of Mississippi
• Mohammad Sanad Abu-Darwish, Al-Balqa Applied University
• Thomas Efferth, Johannes Gutenberg University
• Yan-Hong Wang, University of Mississippi
• Djamila Belouahem-Abed, Institut National De Recherche Forestière
• Samir Benayache, Université des Frères Mentouri
• Babu L. Tekwani, University of Mississippi
• Stephen J. Cutler, University of Mississippi

Department

Pharmacy

Document Type

Article

DOI

10.1016/j.phymed.2017.12.032

Publication Date

2-1-2018

Abstract

Monoamine oxidases (MAOs) are outer mitochondrial membrane flavoenzymes. They catalyze the oxidative deamination of a variety of neurotransmitters. MAO-A and MAO-B may be considered as targets for inhibitors to treat neurodegenerative diseases and depression and for managing symptoms associated with Parkinson's and Alzheimer's diseases.

Relational Format

journal article

Recommended Citation

Larit, F., Elokely, K. M., Chaurasiya, N. D., Benyahia, S., Nael, M. A., León, F., Abu-Darwish, M. S., Efferth, T., Wang, Y.-H., Belouahem-Abed, D., Benayache, S., Tekwani, B. L., & Cutler, S. J. (2018). Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants. Phytomedicine, 40, 27–36. https://doi.org/10.1016/j.phymed.2017.12.032

Accessibility Status

Searchable text