Wernicke’s Area in Autism: rsfMRI study

Author

Sydney OsbarnFollow

Date of Award

Fall 5-9-2020

Document Type

Undergraduate Thesis

Department

Communication Sciences and Disorders

First Advisor

Toshikazu Ikuta

Second Advisor

Gregory Snyder

Third Advisor

John Young

Relational Format

Dissertation/Thesis

Abstract

We investigated the functional connectivity of Wernicke’s Area and its right homologue (Planum Temporale) in individuals with Autism Spectrum Disorder (ASD) and typically developing individuals. We used resting state functional magnetic resonance imaging to analyze these areas in 145 participants from The University of Michigan via ABIDE. As a retest sample, we also used data from a University of Pittsburgh cohort. There is weakened functional connectivity between Wernicke’s Area and Planum Temporale in individuals with ASD as opposed to typically developing individuals. Participants with ASD did not have greater connectivity in other regions compared to the control group. Pragmatics, nonverbalism, speech perception, and receptive language could possibly be affected in individuals with ASD because of the poor functional connectivity in Wernicke’s Area.

Recommended Citation

Osbarn, Sydney, "Wernicke’s Area in Autism: rsfMRI study" (2020). Honors Theses. 1588.
https://egrove.olemiss.edu/hon_thesis/1588

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This work is licensed under a Creative Commons Attribution 4.0 International License.