Date of Award
Communication Sciences and Disorders
We investigated the functional connectivity of Wernicke’s Area and its right homologue (Planum Temporale) in individuals with Autism Spectrum Disorder (ASD) and typically developing individuals. We used resting state functional magnetic resonance imaging to analyze these areas in 145 participants from The University of Michigan via ABIDE. As a retest sample, we also used data from a University of Pittsburgh cohort. There is weakened functional connectivity between Wernicke’s Area and Planum Temporale in individuals with ASD as opposed to typically developing individuals. Participants with ASD did not have greater connectivity in other regions compared to the control group. Pragmatics, nonverbalism, speech perception, and receptive language could possibly be affected in individuals with ASD because of the poor functional connectivity in Wernicke’s Area.
Osbarn, Sydney, "Wernicke’s Area in Autism: rsfMRI study" (2020). Honors Theses. 1588.
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