Honors Theses

Date of Award

Spring 5-2-2021

Document Type

Undergraduate Thesis

Department

Biology

First Advisor

Colin Jackson

Second Advisor

Wayne Gray

Third Advisor

Peter Zee

Relational Format

Dissertation/Thesis

Abstract

The threat of antibiotic resistance is a major problem faced by the healthcare field affecting millions of people and costing tens of thousands of lives annually. Of the potential ways to mitigate this issue the field of antibiotic resistance testing presents an opportunity for significant improvement and benefits. Several methods of such diagnostic processes can yield more informative results than the current commonly used Kirby-Bauer test. However, there are benefits and limitations to each method. In the context of a clinically relevant diagnostic for antibiotic resistance, the microarray platform exhibits the necessary breadth with opportunities to overcome some limitations with further research and development. There is potential for innovation of this method to automate it and optimize its efficiency in a clinical setting for the purpose of antibiotic resistance diagnosis. This presents a hopeful tool that physicians can rely upon to combat antibiotic resistance and improve patient outcomes.

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