Honors Theses
Date of Award
2014
Document Type
Undergraduate Thesis
Department
Chemistry and Biochemistry
First Advisor
Daniell Mattern
Relational Format
Dissertation/Thesis
Abstract
The aim of this research is to investigate the periodination of benzene derivatives that are activated towards electrophilic aromatic substitution. In this research, a successful electrophilic aromatic substitution reaction was completed with procedures that used iodine with silver sulfate as an activating agent in the reaction mixture. The ball-milling technique with N-iodosuccinnimide as the iodinating reagent was also explored. Only one iodine was added onto 4-iodoanisole as the activated benzene derivative. When 2,4-dichloroanisole was the substrate, a small amount of diiodo product accompanied the monoiodo product, but no triiodo (periodinated) product was observed. Nonetheless, the trials of this research give valuable insight into extensions of previously published works that will not facilitate the polyiodination of activated benzene derivatives.
Recommended Citation
Gilbert, Dakota, "An Investigation Into Polyiodination of Activated Benzene Derivatives with Electrophilic Aromatic Substitution Reactions" (2014). Honors Theses. 235.
https://egrove.olemiss.edu/hon_thesis/235
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