Honors Theses

Date of Award

Spring 4-30-2026

Document Type

Undergraduate Thesis

Department

Biomedical Engineering

First Advisor

Thomas Werfel

Second Advisor

Alex Flynt

Relational Format

Thesis

Abstract

This project presents the design and evaluation of PICC-PAL, a wearable assistive device intended to improve independence and usability for patients managing peripherally inserted central catheters (PICC lines) at home. Current at-home PICC line management often requires help due to the fine motor skills needed to connect and secure tubing. This increases reliance on caregivers and introduces potential risks such as infection and dislodgement. Through stakeholder analysis, prior art evaluation, and iterative prototyping, a device was developed to stabilize the PICC line lumen and enable one-handed connection of medical tubing. Throughout the project, multiple design concepts were explored, with the final design consisting of a band-mounted clip system that secures the needleless connector in a fixed position on the patient’s arm. The final prototype was evaluated through sterility testing, flow rate analysis, and mechanical compression testing. The results demonstrated that the device does not increase contamination risk when properly cleaned, does not significantly impact fluid flow, and can withstand forces exceeding those encountered during typical use. The device meets key safety and functional requirements while improving accessibility for patients with limited dexterity. This supports the feasibility of PICC-PAL as a practical solution for enhancing patient independence and safety in at-home PICC line care.

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