Date of Award
2019
Document Type
Thesis
Degree Name
M.S. in Pharmaceutical Science
Department
Pharmaceutics and Drug Delivery
First Advisor
David A. Colby
Second Advisor
David Colby
Third Advisor
Jared H. Delcamp
Relational Format
dissertation/thesis
Abstract
The total synthesis of polyhydroxylated flavones have proven to be challenging, due to the presence of more than one hydroxyl group. Direct cyclization was not successful in any of the attempts. However, by using a silyl protecting group, the cyclization was feasible. Other reactions like the Friedel-Crafts acylation and selective protection of phenols were also difficult.
Recommended Citation
Alkhodier, Reem, "Progress Toward the Synthesis of 3-Methoxyflavones as Potential Antioxidants, Neuroprotective Agents, and Trifluoromethylated 19F NMR Probes" (2019). Electronic Theses and Dissertations. 1574.
https://egrove.olemiss.edu/etd/1574