Electronic Theses and Dissertations

Date of Award

2019

Document Type

Thesis

Degree Name

M.S. in Chemistry

Department

Chemistry and Biochemistry

First Advisor

Jonah Jurss

Second Advisor

Walter Cleland

Third Advisor

Davita L. Watkins

Relational Format

dissertation/thesis

Abstract

The following chapter of this thesis will cover the oxidation of guanine monophosphate (GMP). GMP has been linked to numerous conditions when it is oxidized or damaged. There have been two oxidation pathways suggested in association to the oxidation of GMP: EPT and MS-EPT. The ideal conditions for GMP’s oxidation is still be studied and collected. The study focuses on the acetate versus phosphate buffer, varying base concentration in phosphate buffer, and the varying concentration of ruthenium complex, a redox mediator.

Included in

Chemistry Commons

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