Date of Award
1-1-2024
Document Type
Thesis
Degree Name
M.S. in Engineering Science
First Advisor
Yixin Chen
Second Advisor
Charles W. Walter
Third Advisor
Hong Xiao
Relational Format
dissertation/thesis
Abstract
Protein structure comparison and our understanding of protein sequence and structure relationships are intertwined. In this work, I use the TSR-based key generation algorithm to develop a model for relating sequence and structure. I develop embeddings for the sequence-based keys and the structure-based keys as the basis for a translation model between the two sets of keys, evaluating the efficacy of local and global embedding generation techniques in the context of the TSR-based comparison method.
Recommended Citation
Swensen, Arianna Nicole, "Modeling the Relationship Between Protein Sequence and Structure Using Triangular Spatial Relationship-Based Keys" (2024). Electronic Theses and Dissertations. 2883.
https://egrove.olemiss.edu/etd/2883