Electronic Theses and Dissertations

Date of Award

1-1-2025

Document Type

Dissertation

Degree Name

Ph.D. in Psychology

First Advisor

Todd Smitherman

Second Advisor

Aaron Lee

Third Advisor

Laura Dixon

School

University of Mississippi

Relational Format

dissertation/thesis

Abstract

Migraine is a prevalent and disabling pain condition that affects the central nervous system, and women are disproportionately affected. Migraine is often comorbid with psychiatric disorders, such as depression and anxiety disorders, which compound the pain experience. Psychosocial correlates of migraine (i.e., fear of pain, pain catastrophizing) that are often observed in individuals with comorbid psychiatric disorders further contribute to the experience of pain and resulting headache-related disability. Social factors (i.e., loneliness and social exclusion) differentially affect pain responses in individuals with chronic pain; however, no literature to date has explored the effects of social exclusion on pain in migraine. The present study aimed to examine the relationship between social exclusion and pain experience among females with migraine. Participants with and without migraine were randomly assigned to a social exclusion or inclusion manipulation and then completed a cold pressor task. We hypothesized that baseline loneliness would predict pain responses and that participants with migraine would have lower pain threshold and tolerance compared to controls. We also hypothesized that exclusion (compared to inclusion) would increase pain among controls but decrease pain among migraine participants due to a previously documented “buffering effect.” Though migraine participants demonstrated lower pain tolerance compared to controls, there was no relation between loneliness and pain and no interaction effects between migraine status and social exclusion manipulation on pain responses. Despite a large sample size and strong experimental design, social exclusion did not affect pain responses in the current study. Given the variability of responses to social exclusion among chronic pain populations, further research is warranted to elucidate the potential importance, or lack thereof, of social exclusion within migraine.

Available for download on Thursday, November 18, 2027

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