"Exploring the Incidence of Synthetic versus Non-Synthetic Cannabinoid-" by Ruaa Al-Juboori, Zachariah Francois et al.
 

Document Type

Report

Publication Date

2-7-2025

Abstract

Cannabinoids, including synthetic and non-synthetic variants, are associated with diverse mental health outcomes including the development of psychotic symptoms. While non-synthetic cannabinoids such as THC are well-studied, the stronger affinity of synthetic cannabinoids for cannabinoid receptors may lead to more severe and unpredictable health outcomes, including acute psychosis. Therefore, the objective of this scoping review is to investigate if the literature reported differences in the incidence of synthetic cannabinoid-induced psychosis versus non-synthetic cannabinoid-induced psychosis and quantify these differences if present. Following the JBI guidelines for scoping reviews, we will conduct a literature search across multiple databases including PubMed, PsycINFO, Scopus, and Web of Science, covering publications from January 2008 to the present. Data will be synthesized narratively, with supplementary tables and charts summarizing key comparisons.

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report

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