Honors Theses
Date of Award
Spring 5-14-2023
Document Type
Undergraduate Thesis
Department
Biology
First Advisor
Toshikazu Ikuta
Second Advisor
Hyejin Park
Third Advisor
Alberto Jose Del Arco Gonzalez
Relational Format
Dissertation/Thesis
Abstract
Individuals with autism spectrum disorder (ASD) can have abnormal responses and hypersensitivity to sounds (Haesen et al., 2011). ASD is also related to inattentive, hyperactive, and impulsive behaviors (Bradley & Isaacs, 2006). One study by Stansberry et al. (2022) found that a higher fractional anisotropy (FA) of interhemispheric auditory white matter is associated with higher impulsivity. Our study examined the interhemispheric auditory tract (IAT) to determine whether it is impacted by ASD. We used diffusion tensor imaging (DTI) data from Autism Brain Imaging Data Exchange utilizing two datasets so that we could replicate primary findings. We first isolated the IAT and examined Fractional Anisotropy, Axial Diffusivity, Radial Diffusivity (RD), and Mean Diffusivity within the IAT. The ASD group was found to have lower FA and a higher RD of the IAT than the control group. It is suggested that the left and right auditory cortices may communicate less in the ASD population than the others.
Recommended Citation
Long, Josie, "The Interhemispheric Auditory Tract Connectivity and Autism Spectrum Disorder" (2023). Honors Theses. 2848.
https://egrove.olemiss.edu/hon_thesis/2848
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This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
