Document Type
Oral Presentation
Location
Oxford Convention Center, 102 Ed Perry Boulevard Oxford, MS 38655
Event Website
https://oxfordicsb.org/
Start Date
15-4-2024 4:30 PM
End Date
15-4-2024 5:30 PM
Description
Before the National Center for Natural Products Research (NCNPR) existed, I was Director of a USDA weed management lab. Two of my interests were natural products as herbicides and the chemical ecology of weed/crop interactions (allelopathy). Dr. James McChesney and I had several conversations about his vision for the NCNPR on the University of Mississippi campus. I was very interested in becoming a part of this, as his plan was to have a USDA lab that would study natural products for use in food and agriculture as part of the center. The USDA Agricultural Research Service established the Natural Product Utilization Research Unit (NPURU) as part of the NCNPR in 1996, when I arrived here. Most NPURU research has dealt with the use of natural products for pest management, but some of the most successful work has been on nutraceuticals. The late Agnes Rimando published extensively on the health benefits of pterostilbene, generating several patents. Her work, much of it with Univ. of Miss. colleagues, showed beneficial effects of pterostilbene as an antioxidant, antiaging, anti-cholesterol, anticancer, and antidiabetic compound. 2-Methylisoborneol from cyanobacteria bioaccumulates in the flesh of aquaculture-produced fish. Collaborative work of NCNPR and NPURU led to the patenting of a selective cyanobactericide that selectively kills cyanobacteria without harming beneficial green algae. This product worked well in field trials in eliminating MIB of harvested fish. Several patents have been obtained for novel natural-product-based fungicides, herbicides, insecticides, and insect repellents. This work led to the discovery of much-needed new molecular target sites of pesticides and determination of one that was unknown for many years. Long-range research is being conducted to produce crops that produce their own herbicides. Current cooperation extends to novel natural product-based pesticides that are being patented for consideration by the pest management industry.
Recommended Citation
Duke, Stephen O., "Natural products in food and agriculture" (2024). Oxford ICSB. 11.
https://egrove.olemiss.edu/icsb/2024_ICSB/Schedule/11
Publication Date
April 2024
Accessibility Status
Searchable text
Included in
Natural products in food and agriculture
Oxford Convention Center, 102 Ed Perry Boulevard Oxford, MS 38655
Before the National Center for Natural Products Research (NCNPR) existed, I was Director of a USDA weed management lab. Two of my interests were natural products as herbicides and the chemical ecology of weed/crop interactions (allelopathy). Dr. James McChesney and I had several conversations about his vision for the NCNPR on the University of Mississippi campus. I was very interested in becoming a part of this, as his plan was to have a USDA lab that would study natural products for use in food and agriculture as part of the center. The USDA Agricultural Research Service established the Natural Product Utilization Research Unit (NPURU) as part of the NCNPR in 1996, when I arrived here. Most NPURU research has dealt with the use of natural products for pest management, but some of the most successful work has been on nutraceuticals. The late Agnes Rimando published extensively on the health benefits of pterostilbene, generating several patents. Her work, much of it with Univ. of Miss. colleagues, showed beneficial effects of pterostilbene as an antioxidant, antiaging, anti-cholesterol, anticancer, and antidiabetic compound. 2-Methylisoborneol from cyanobacteria bioaccumulates in the flesh of aquaculture-produced fish. Collaborative work of NCNPR and NPURU led to the patenting of a selective cyanobactericide that selectively kills cyanobacteria without harming beneficial green algae. This product worked well in field trials in eliminating MIB of harvested fish. Several patents have been obtained for novel natural-product-based fungicides, herbicides, insecticides, and insect repellents. This work led to the discovery of much-needed new molecular target sites of pesticides and determination of one that was unknown for many years. Long-range research is being conducted to produce crops that produce their own herbicides. Current cooperation extends to novel natural product-based pesticides that are being patented for consideration by the pest management industry.
https://egrove.olemiss.edu/icsb/2024_ICSB/Schedule/11