This article examines processes of globalization and local development particularly how agribusiness, in alliance with the federal government, has shaped recent economic, demographic, and social changes in the Mississippi Delta region. The author examines how globalization shapes conditions in the flatland Mississippi Delta and argues that globalization creates conditions at the local level that suppress economic opportunities for many residents. The final section identifies the implications for public policy formulation and development practice on both the global and local levels.The author offers recommendations on how the region can “take the high road” to ease persistent poverty.

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