The annual National Writing Project in the South is a regional conference focused on writing instruction and teacher leadership. Its location alternates between Oxford, Mississippi (University of Mississippi) and Greenville, South Carolina (Clemson University), depending on the host institution for each year.

The University of Mississippi Writing Project and the Upstate Writing Project at Clemson University are among 160 sites of the National Writing Project, a "network of teachers, university faculty, researchers, writers, and community educators working to advance writing and the teaching of writing."