Document Type

Oral Presentation

Location

Oxford Convention Center, 102 Ed Perry Boulevard Oxford, MS 38655

Event Website

https://oxfordicsb.org/

Start Date

16-4-2024 2:00 PM

End Date

16-4-2024 2:30 PM

Description

Natural Products (NP) are on the rise across the world, driven by economic, environmental, health and societal needs. An increasing focus has been placed on the role of boglands within climate change as peatlands store 1/3 of the world’s soil carbon and provide water storage. With our project ‘Unlocking Nature’s Pharmacy’ we aim to increase public awareness and drive Ireland towards a bioeconomy where Natural Product Science (NPS) plays a key role. At the NatPro Centre, the Trinity Centre for Natural Products Research, we use systems-based approaches (SBA), for example looking at the bogs of Ireland, to identify innovative bio-based solutions to support health and enable change on a scientific, social and governmental level. Using multidisciplinary research ranging from ethnopharmacology to systems pharmacology, we present scientific knowledge linked to the cultural, therapeutic and commercial potential of native species growing on boglands. We have identified key functional bioactives from over 70 plant species, the majority being angiosperms, bryophytes and lichens. We have investigated these species using chemical analysis, metabolomic profiling and genomic studies, as well as in vitro, in vivo and ex vivo models. To date circa 10 leads have progressed to advanced screening, with two species being considered for potential commercialisation. The project is embedded in NatPro sustainability approaches, green practices and quality systems, which complement laboratory practices. NatPro acts as a beacon for education, government and industry engagement, integrating innovative approaches, scientific knowledge and regulation to inform policy and to build capacity among NP stakeholders, including businesses, communities and students, to support the Irish transition to a bioeconomy. We use NPS to drive transformative practices to address urgent needs. Here we present a systemic view from bogs to Irish bioeconomy: potted history, current status and future prospects.

Comments

This research is undertaken as part of the Unlocking Nature’s Pharmacy from Bogland Species (UNPBS) Project under grant number DOJProject209825, funded by the Dept. of Justice, Ireland.

Publication Date

April 2024

Accessibility Status

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Apr 16th, 2:00 PM Apr 16th, 2:30 PM

Natural Products Ireland: from Bioactives to the Bioeconomy - A Systems-Based Approach

Oxford Convention Center, 102 Ed Perry Boulevard Oxford, MS 38655

Natural Products (NP) are on the rise across the world, driven by economic, environmental, health and societal needs. An increasing focus has been placed on the role of boglands within climate change as peatlands store 1/3 of the world’s soil carbon and provide water storage. With our project ‘Unlocking Nature’s Pharmacy’ we aim to increase public awareness and drive Ireland towards a bioeconomy where Natural Product Science (NPS) plays a key role. At the NatPro Centre, the Trinity Centre for Natural Products Research, we use systems-based approaches (SBA), for example looking at the bogs of Ireland, to identify innovative bio-based solutions to support health and enable change on a scientific, social and governmental level. Using multidisciplinary research ranging from ethnopharmacology to systems pharmacology, we present scientific knowledge linked to the cultural, therapeutic and commercial potential of native species growing on boglands. We have identified key functional bioactives from over 70 plant species, the majority being angiosperms, bryophytes and lichens. We have investigated these species using chemical analysis, metabolomic profiling and genomic studies, as well as in vitro, in vivo and ex vivo models. To date circa 10 leads have progressed to advanced screening, with two species being considered for potential commercialisation. The project is embedded in NatPro sustainability approaches, green practices and quality systems, which complement laboratory practices. NatPro acts as a beacon for education, government and industry engagement, integrating innovative approaches, scientific knowledge and regulation to inform policy and to build capacity among NP stakeholders, including businesses, communities and students, to support the Irish transition to a bioeconomy. We use NPS to drive transformative practices to address urgent needs. Here we present a systemic view from bogs to Irish bioeconomy: potted history, current status and future prospects.

https://egrove.olemiss.edu/icsb/2024_ICSB/Schedule/17