Document Type

Oral Presentation

Location

Oxford Conference Center

Event Website

https://oxfordicsb.org/

Start Date

21-4-2026 11:10 AM

End Date

21-4-2026 11:30 AM

Description

Quality control of botanicals is approaching a breaking point. Regulators, industry, and pharmacists are now forced to answer questions faster and at larger scale than ever before: What plant is actually in the product? Is it the right species—or a look-alike? Is it pure or adulterated? Is it safe? Is the chemistry consistent? And how can labs make confident decisions when analytical capacity and staffing are finite? This presentation demonstrates how modern HPTLC— far beyond its historical role as a simple identity test— now provides clear, interpretable chemical evidence that supports analyst with a practical tool for risk-based surveillance of food and supplement products. Its adoption in the African Herbal Pharmacopoeia, USP, European Pharmacopoeia, and International Pharmacopoeia demonstrates how HPTLC is already being used to support analysts for decision-making. Case examples show HPTLC resolving species substitutions and adulteration, exposing fatty oil adulteration, and detecting unsafe components in finished products—all with workflows streamlined enough for routine QC. New HPTLC concepts—including advanced imaging systems, and advanced software tools enabling quantitation and supporting the Ph. Eur. 2.8.25 revision— empowers HPTLC to serve as a first-line screen. With ongoing collaborations spanning Indonesia, Ph. Eur., WHO, USP, and national labs, HPTLC is rapidly emerging as a harmonizing force across regulatory systems. The conclusion is direct: HPTLC now provides the scalability, visual honesty, and actionable outcomes needed to keep the botanical market safe. The only remaining question is whether regulators and industry are ready to use the tool that already works.

Comments

Dr. Do earned her PhD in Analytical Chemistry from the University of Nice, France. She currently serves as Chief Scientific Officer at CAMAG (Switzerland) and as Secretary General of the HPTLC Association. Her expertise lies in analytical chemistry with a focus on natural products and synthetic samples, particularly in the development and application of HPTLC methods. She has led and coordinated international collaborative projects with regulatory bodies (including the African Pharmacopoeia, USP, Ph. Eur., and KFDA), academia, and industry, contributing significantly to the advancement of analytical science. Dr. Do is the author of numerous scientific publications in leading journals (e.g., Food Analytical Methods, Journal of Planar Chromatography, Journal of Chromatography A), co-author of two books and one book chapter, and is frequently invited as a speaker at international conferences. She currently serves as an Expert Volunteer for the United States Pharmacopeia (USP) for the 2025–2030 cycle, participates as an expert in three European Pharmacopoeia working groups, is a member of ISO/TC 249, and contributes to two expert committees of the Swiss Pharmacopoeia, advancing global pharmacopoeial standards.

Publication Date

April 2026

Accessibility Status

Screen reader accessible, Searchable text

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Apr 21st, 11:10 AM Apr 21st, 11:30 AM

HPTLC: The New Front Line of Global Botanical Surveillance

Oxford Conference Center

Quality control of botanicals is approaching a breaking point. Regulators, industry, and pharmacists are now forced to answer questions faster and at larger scale than ever before: What plant is actually in the product? Is it the right species—or a look-alike? Is it pure or adulterated? Is it safe? Is the chemistry consistent? And how can labs make confident decisions when analytical capacity and staffing are finite? This presentation demonstrates how modern HPTLC— far beyond its historical role as a simple identity test— now provides clear, interpretable chemical evidence that supports analyst with a practical tool for risk-based surveillance of food and supplement products. Its adoption in the African Herbal Pharmacopoeia, USP, European Pharmacopoeia, and International Pharmacopoeia demonstrates how HPTLC is already being used to support analysts for decision-making. Case examples show HPTLC resolving species substitutions and adulteration, exposing fatty oil adulteration, and detecting unsafe components in finished products—all with workflows streamlined enough for routine QC. New HPTLC concepts—including advanced imaging systems, and advanced software tools enabling quantitation and supporting the Ph. Eur. 2.8.25 revision— empowers HPTLC to serve as a first-line screen. With ongoing collaborations spanning Indonesia, Ph. Eur., WHO, USP, and national labs, HPTLC is rapidly emerging as a harmonizing force across regulatory systems. The conclusion is direct: HPTLC now provides the scalability, visual honesty, and actionable outcomes needed to keep the botanical market safe. The only remaining question is whether regulators and industry are ready to use the tool that already works.

https://egrove.olemiss.edu/icsb/2026_ICSB/Schedule/8