Graduate Theses and Dissertations in Pharmaceutical Science

 

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Theses/Dissertations from 2018

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Feasibility of AquasolveTM HPMC-AS Lg via Hot-melt Extrusion: Effect of Pressurized CO2 on Physico-mechanical Properties, Mashan Almutairi

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Novel Applications of Hot-Melt Extrusion Technology, Ajinkya Moreshwar Bhagurkar

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Functionality And Role Of Different Fatty Alcohols In Topical O/W Cream Formulation, Supriya Bhide

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Crystalline Salt Formation of an Acidic Drug Indomethacin Using Hot Melt Extrusion Technology, Mustafa Bookwala

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Synthetic Investigation of Natural Products Causing Dopaminergic Neurodegeneration, Michael John Cunningham

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Predictors Of Dental Opioid Analgesic Prescribing, Opioid Use And Dental Emergency Department Visits In The Mississippi Medicaid Population, Chukwuebuka Dibie

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Topical Formulation For Stimulating Sweat Secretion as an Alternative to Iontophoresis, Tasnim Fatima

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Preparation and Evaluation of Cefuroxime Axetil Gastro-Retentive Floating Drug Delivery System for Improved Delivery via Hot-Melt Extrusion Technology, Rahul Madhukar Lalge

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Polymer Based Delivery Of Doxycycline Hyclate For The Prevention Of Peri-Implant Mucositis Infection, Sagar Deepak Sawant

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Preparation And Evaluation Of Valacyclovir Hydrochloride Ocular Inserts By Hot Melt Extrusion Technique, Gauri Shadambikar

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Development and Characterization of Fluocinolone Acetonide Loaded Nanosized Lipid Carriers for Ocular Delivery via Subconjunctival Route: Synergistic Effect of Vitamin a Palmitate, Bhavik Soneta

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Fluorinated Organic Molecules for Medicinal Applications, Munia Sowaileh

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The Role of Brand Name Fluency: A Pharmaceutical Marketing Perspective, David Wamble

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Synthesis and Characterization of Redox-Sensitive Polymer and Prodrug for Targeted Drug Delivery, Chang-Hee Whang

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A Novel Acetaminophen Soft-Chew Formulation Produced Via Hot Melt Extrusion With Inline Near-Infrared Monitoring As A Process Analytical Technology Tool, Pengchong Xu

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Novel Application of Twin Screw Extruder on Production of Diverse Formulations, Xingyou Ye

Theses/Dissertations from 2017

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Preparation And Characterization Of Acitretin-Loaded Niosomes For Psoriasis Treatment, Marey Abdulmootani Almaghrabi

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Lipid Based Frameworks And Topical Ocular Inserts For The Delivery Of Small Molecule Therapeutics To The Posterior Segment Of The Eye, Sai Prachetan Balguri

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Regulation of the kRAS Promoter in Pancreatic Cancer by Proteins and Small Molecules, Harshul Batra

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Burden Of Depression Among Individuals With Irritable Bowel Syndrome(Ibs) In The Medicaid Population, Kaustuv Bhattacharya

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Characterizing the Developmental and Reproductive Toxicities of Cannabidiol and Δ9-Tetrahydrocannabinol, Dennis Ray Carty

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The Decision To Pursue Pharmacy Residency Training: Motivators, Barriers, And The Fear Of Missing Out (Fomo), Ashley Stubblefield Crumby

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Phytochemical Investigation of Psychoactive Medicinal Plants for the Treatment of Neurological Disorders, Vedanjali Gogineni

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Nucleic acid clamp-mediated transcriptional and translational modulation of oncogenes via the stabilization of G-quadruplexes, Taisen Hao

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Biochemical and Molecular Assessment of Toxicity of Primaquine Metabolites on Erythrocytes, Jagrati Jain

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Development of Phenotypic Drug Discovery Models for Tropical Parasitic Diseases, Surendra Kumar Jain

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Synthesis, Chemistry, Biological Evaluation And Structure-Activity Relationships Of Rac- And Chiral 6-Desmethyl-5Β –Hydroxy-D-Secoartemisinin And Analogs, Mohamed Elsideiq Jihan

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Molecular Characterization of the Opioid Receptors: Design, Development, and Preclinical Evaluation of Salvinorin A-Based Molecular Probes., Adam Keasling

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Synthesis and characterization of pH/temperature dual sensitive multiblock copolymer for drug delivery, Hyung Kyung Lee

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G-Quadruplexes As Molecular Targets For Transcriptional Control, Rhianna Kyelle Morgan

Predictors Of Medication Nonadherence In Children/Adolescents With Attention Deficit Hyperactivity Disorder (Adhd) In Mississippi Medicaid Program, Wahidullah Noori

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Patient Friendly Formulations Utilizing Hot Melt Extrusion Technology, Manjeet Bhagwan Pimparade

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Identification Of Stimulant Misuse And Malingering Of Symptoms Of Attention Deficit Hyperactivity Disorder, Sujith Ramachandran

Theses/Dissertations from 2016

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Saffron extract and its active constituents as preventative and/or treatment agents for prostate cancer using in vitro and in vivo models, FAISAL FAYIH ALBAQAMI

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Critical Quality Attributes of Topical Semi-solid Dosage Forms: Solvent Activity, Muralikrishnan Angamuthu

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Evaluation and enhancement of physical stability of amorphous solid dispersions, XIN FENG

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Payer Perspectives On Preemptive Pharmacogenetic Testing, Nicholas Keeling

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Novel approaches for ungual and trans-ungual delivery of drugs, Avadhesh Singh Kushwaha

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Targeting protein kinases to manage or prevent Alzheimer’s disease, Manal A. Nael

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Biological And Psychosocial Risk Factors Of Stroke In African Americans Enrolled In The Jackson Heart Study (Jhs), Sasikiran Nunna

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Hot-melt extrusion: A versatile pharmaceutical technology, Hemlata Patil

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Measuring And Understanding Health-Related Quality Of Life Among Adult Patients With Hemophilia, Ruchitbhai Mukesh Shah

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Biological and Chemical Investigation of Panamanian Plants for Potential Utility against Metabolic Syndrome, Yelkaira Vasquez

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Exploring new chemical entities from traditional medicine: Docking, synthesis and specific bioactivities, Chinni Yalamanchili

Theses/Dissertations from 2015

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Non-invasive drug delivery to the posterior segment of the eye: Development of formulation strategies and evaluation of ocular distribution and pharmacological activity, Goutham Reddy Adelli

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Effects of benzo[a]pyrene and CYP19a1b knockdown on zebrafish development, KHALID M. ALHARTHY

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Influence of hot melt extrusion processing parameters on the properties of a pharmaceutical formulation, Saad M. Alshahrani

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Design, synthesis, and biological evaluation of sigma receptors (σRS) ligands as potential pharmacotherapy for cancer and drug addiction, Walid Alsharif

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Versatility of hot-melt extrusion for dosage form design, Sultan Mohammad Alshehri

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Solubility enhancement, mechanical properties and taste masking of poorly water soluble compounds by optimizing hot melt extrusion processing, Abdullah Saud Alshetaili

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Characterizing the Innate Immunity in the Hawaiian Coral Montipora capitata, Melinda S. Ansley

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Influence of novel techniques on solubility, mechanical properties and permeability via hot melt extrusion technology, Eman A. Ashour

Development Of The Medication Non-Adherence Scale (Mnas) And The Medication Non-Persistence Scale (Mnps), Amod Sudhir Athavale

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Design, Synthesis And Cannabinoid Receptor Activity Of Benzofuran Ligands, Eric William Bow

Ehtnobotanical- And Chemometric-Guided Investigation Of Phytolacca Americana L., Michael Chan

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Predictors Of Use Of Hydroxyurea And Its Impact On Clinical And Economic Outcomes Among Children With Sickle Cell Disease, Manasi Datar

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Primary Care Providers' Provision Of Therapeutic Lifestyle Change Counseling For Patients With Cardiovascular Risk, Tristen Jackson

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Quality of life and healthcare utilization and costs among adults with autism, Krutika Maulik Jariwala-Parikh

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Health Utility Assessment Among Caregivers of Individuals with Multiple Sclerosis, Namita Joshi

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Transdermal Iontophoretic Delivery Of Lipophilic Drugs, Abhishek Juluri

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Screening Of Natural Products For Their Effect On Kallikrein-Kinin System: Potential Implications In The Treatment Of Hereditary Angioedema, Hassan Abdu Madkhali

Effect Of Risk Evaluation And Mitigation Strategies (Rems) On Utilization Of Thiazolidinediones In A Medicaid Population, Clive Mario Mendonca

Novel Delivery Systems For Iron Replenishment, Naresh Modepalli

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Progress Toward The Total Synthesis Of The Natural Product Herbicide Ascaulitoxin Aglycone, Jeffery Brian Morgan

Endangered Plant Species For Potential Drug Leads And Anticancer Prototypes For Treatment Of Breast And Pancreatic Cancers, Joonseok Oh

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Protein-ligand interaction studies and identification of new drug-like hits as cannabinoid receptor modulators, Pankaj Pandey

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Lipid & surfactant based systems for improved delivery of poorly soluble APIs, Sri Satyasai Nagendra Babu Punyamurthula

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Youth With Type 1 Diabetes Mellitus: An Examination Of Adolescents’ Illness Perceptions And Associated Impact On Health-Related Quality Of Life, Zainab Shahpurwala

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Evaluation of inhibitors of histone deacetylases as potential neurotrophic agents, Surabhi Shukla

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Discovery of Alternative Artemisinin Binding Sites in Plasmodium falciparum ATPase-6, Shuneize Elizabeth Slater

Evaluation Of Novel Ligands For Opioid Receptors, Amer Hussien Tarawneh

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Impact Of Refill Synchronization On Medication Adherence For Chronic Diseases, Divya Verma

Theses/Dissertations from 2014

Evaluation Of Wild Yam (Dioscorea Villosa) As A Demethylating Agent And Its Anti Metastatic Activity In Human Breast Cancer Cells, Pranapda Aumsuwan

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Cranberry metabolites with urinary anti-adhesion activity, Christina M. Coleman

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Effects of nanosilver and silver nitrate exposure on fathead minnows (Pimephales promelas) and zebrafish (Danio rerio), Adam D. Hawkins

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Secondary Metabolite Production By An Endophytic Bacillus sp. from Platanus Occidentalis, Michael C. James

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Solubility Enhancement and Precipitation Inhibition of Poorly Water Soluble Compounds Utilizing Hot Melt Extrusion Technology, Jiannan Lu

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Management of breast cancer in the Medicaid population, Rohan Mahabaleshwarkar

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Intranasal delivery of therapeutics targeted to CSF and Brain, Prashanth Manda

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The Efficacy Of Prostaglandin Synthase Inhibition On Attenuating Pressure Overload Induced Cardiac Remodeling, Krishna T. Nagalla

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Pharmacists' Preparedness For Acute Medical Emergencies, James W. Parrett

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Solubility Enhancement via Melt Extrusion: Drug-polymer Solubility, Physicochemical Characterization and Quality by Design, Ketaki Patwardhan

Determining Physician And Patient Characteristics That Predict The Use Of Atypical Antipsychotics In Children With Mental Health Disorders, Sujith Ramachandran

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Customer Tolerance In Community Pharmacy, Philip Everett Schwab

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Characterization of Prolylcarboxypeptidase Expression Pattern in Rat Cardiomyocytes in Nutrition Overload Conditions, Tahmineh Tabrizian

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Structure, Synthesis and Biological Activity of Harmful Algal Bloom Toxins from Karlodinium sp. and Exploration of Microbial Derived Natural Products, Amanda Leigh Waters

Theses/Dissertations from 2013

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Structural Characterization And Bioactivity Of Cranberry Oligosaccharides, Kimberly M. Auker

Dual Targeting Ligands Of Sigma Receptors And Dopamine Transporters As Potential Pharmacotherapy For Cocaine Abuse, Shivangi Awasthi

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Concurrent Adherence To Multiple Chronic Disease Medications: Examining The Behavior And Issues Concerning Its Measurement, Ram Sankar Basak

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Benzo[a]pyrene effects on Fundulus heteroclitus reproductive endpoints, Frank Booc

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Molecular modeling and SAR studies of CDK5/p25 selective inhibitors, Arindam Chatterjee

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Synthesis Of Natural Product-Based Sphingosine Derivatives, Zarana Daksh Chauhan

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Potential Natural Product Phosphodiesterase Inhibitors, Michael John Cunningham

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Individual And Population Responses Of The Caribbean Sponge, Aplysina Cauliformis, To Natural And Anthropogenic Stressors, Cole Gregory Easson

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Protein kinases: Structure modeling, inhibition, and protein-protein interactions, Khaled M. Elokely

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Role of the Endocannabinoid System in Cardiac Remodeling, Monica Gole

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Perspectives On Ethanol Toxicity In Medaka Embryogenesis And Possible Protection By Asian Ginseng (Panax Ginseng): Histological And Biochemical Analysis, Mona Hamdi Haron

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Metabolic Stability And Pharmacokinetics In Lead Optimization Of Potential Anti-Psychostimulant Pharmacotherapies, Seshulatha Jamalapuram

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The design, synthesis, and biological evaluation of aplysinopsin analogs as potential neuromodulators, Kevin Lewellyn

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Impact Of Time-Varying And Time-Invariant Measures Of Adherence To Secondary Prevention Therapies Post-Acute Myocardial Infarction: An Application Of Marginal Structural Models (Msms), Tasneem Taher Lokhandwala