Graduate Theses and Dissertations in Pharmaceutical Science

 

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Theses/Dissertations from 2019

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Progress Toward the Synthesis of 3-Methoxyflavones as Potential Antioxidants, Neuroprotective Agents, and Trifluoromethylated 19F NMR Probes, Reem Alkhodier

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Phytochemical Investigation and Drug Interaction Potential of Cyanotis vaga, Ibrahim Almarabi

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Characterization of Drug-Loaded Milled Extrudate Particles Produced by Hot Melt Extrusion Technology for Dry Powder Inhalers, Ahmed Almotairy

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Development and Characterization of Sustained-Release Formulations via Novel Hot Melt Extrusion Techniques, Bjad Khalaf Almutairy

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Synthesis of Fluoroflavones as Potential Neuroprotective Agents, Maali Alshammari

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Developing Zebrafish as an In Vivo Model to Screen Compounds for Anti-Cancer Activity in Human Breast Cancer, Trisha Dhawan

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Safety Assessment and Chemical Fingerprint Analysis of Medicinal Plants Commonly Consumed As Herbal Teas; Rooibos (Aspalathus Linearis) and Moringa (Moringa Oleifera), Omer I. Fantoukh

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Design of Thermosensitive Hydrogel for Extended-Release of Praziquantel, Sheng Feng

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Formulation Development of Natamycin Loaded Nanoemulsion for Ocular Drug Delivery, Kanika Goel

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Pharmacokinetic Study of Novel Anthraquinone Analogues, Yuhan Guo

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Development of Controlled Release Oral Dosages by Density Gradient Modification Using 3D Printing Technologies, Zhiqing Hu

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Formulation Strategies to Address Physiological and Anatomical Constraints for Improved Topical Ocular Drug Delivery, Karthik Yadav Janga

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Nanosuspension Based Electrolyte Sensitive In Situ Gel for Topical Ocular Delivery of Natamycin, Poorva H. Joshi

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Comparative Effectiveness and Safety of Non-Vitamin K Antagonists Oral Anticoagulants and Warfarin in Elderly Patients with Non-Valvular Atrial Fibrillation and Diabetes, Siddhi Korgaonkar

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PEGylated Nanostructured Lipid Carries for Amphotericin B Ocular Delivery, Prit Manish Lakhani

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Effect of Solvent Interaction & Soluble Microneedles on Skin Permeability to Drug Molecules, Abhijeet Maurya

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Novel Applications of Hot-Melt Extrusion Technology in Trans-Buccal and Topical Drug Delivery Systems, Nicole Mendonsa

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Synthesis of a Novel Surface Active, Light Sensitive Polymer for Encapsulation and Delivery of Paclitaxel, Amit Raviraj Pillai

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In-Situ Gel of Cyclosporine A – Loaded Solid Lipid Nanoparticles for Topical Occular Delivery for Dry Eye Disease, Samir Shyambabu Senapati

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Investigation of Theophylline Nicotinamide Pharmaceutical Co-Crystals Utilizing Hot Melt Extrusion, Priyanka Srinivasan

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Formulation Development, Preclinical Testing, and Primary Packaging Optimization for Cannabinoids and Other Therapeutics, Pranjal Taskar

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Optimization and Characterization of Hot-Melt Extruded Anti-Inflammatory and Local Anesthetic Bio-Adhesive Semisolid Formulation Using Design of Experiments (DoE), Rishi Chinmay Thakkar

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Application of Quality by Design and Process Analytical Technology towards Hot-Melt Extrusion Processes, Priyanka Thipsay

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Development of Continuous Manufacturing Process of Acyclovir Ointment Using Hot-Melt Extrusion, Rui Wang

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Novel Application of Melt Extrusion and Additive Manufacturing on Developing Diverse Dosages, Jiaxiang Zhang

Theses/Dissertations from 2018

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Feasibility of AquasolveTM HPMC-AS Lg via Hot-melt Extrusion: Effect of Pressurized CO2 on Physico-mechanical Properties, Mashan Almutairi

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Novel Applications of Hot-Melt Extrusion Technology, Ajinkya Moreshwar Bhagurkar

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Functionality And Role Of Different Fatty Alcohols In Topical O/W Cream Formulation, Supriya Bhide

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Crystalline Salt Formation of an Acidic Drug Indomethacin Using Hot Melt Extrusion Technology, Mustafa Bookwala

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Synthetic Investigation of Natural Products Causing Dopaminergic Neurodegeneration, Michael John Cunningham

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Predictors Of Dental Opioid Analgesic Prescribing, Opioid Use And Dental Emergency Department Visits In The Mississippi Medicaid Population, Chukwuebuka Dibie

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Topical Formulation For Stimulating Sweat Secretion as an Alternative to Iontophoresis, Tasnim Fatima

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Preparation and Evaluation of Cefuroxime Axetil Gastro-Retentive Floating Drug Delivery System for Improved Delivery via Hot-Melt Extrusion Technology, Rahul Madhukar Lalge

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Polymer Based Delivery Of Doxycycline Hyclate For The Prevention Of Peri-Implant Mucositis Infection, Sagar Deepak Sawant

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Preparation And Evaluation Of Valacyclovir Hydrochloride Ocular Inserts By Hot Melt Extrusion Technique, Gauri Shadambikar

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Development and Characterization of Fluocinolone Acetonide Loaded Nanosized Lipid Carriers for Ocular Delivery via Subconjunctival Route: Synergistic Effect of Vitamin a Palmitate, Bhavik Soneta

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Fluorinated Organic Molecules for Medicinal Applications, Munia Sowaileh

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The Role of Brand Name Fluency: A Pharmaceutical Marketing Perspective, David Wamble

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Synthesis and Characterization of Redox-Sensitive Polymer and Prodrug for Targeted Drug Delivery, Chang-Hee Whang

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A Novel Acetaminophen Soft-Chew Formulation Produced Via Hot Melt Extrusion With Inline Near-Infrared Monitoring As A Process Analytical Technology Tool, Pengchong Xu

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Novel Application of Twin Screw Extruder on Production of Diverse Formulations, Xingyou Ye

Theses/Dissertations from 2017

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Preparation And Characterization Of Acitretin-Loaded Niosomes For Psoriasis Treatment, Marey Abdulmootani Almaghrabi

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Lipid Based Frameworks And Topical Ocular Inserts For The Delivery Of Small Molecule Therapeutics To The Posterior Segment Of The Eye, Sai Prachetan Balguri

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Regulation of the kRAS Promoter in Pancreatic Cancer by Proteins and Small Molecules, Harshul Batra

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Burden Of Depression Among Individuals With Irritable Bowel Syndrome(Ibs) In The Medicaid Population, Kaustuv Bhattacharya

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Characterizing the Developmental and Reproductive Toxicities of Cannabidiol and Δ9-Tetrahydrocannabinol, Dennis Ray Carty

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The Decision To Pursue Pharmacy Residency Training: Motivators, Barriers, And The Fear Of Missing Out (Fomo), Ashley Stubblefield Crumby

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Phytochemical Investigation of Psychoactive Medicinal Plants for the Treatment of Neurological Disorders, Vedanjali Gogineni

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Nucleic acid clamp-mediated transcriptional and translational modulation of oncogenes via the stabilization of G-quadruplexes, Taisen Hao

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Biochemical and Molecular Assessment of Toxicity of Primaquine Metabolites on Erythrocytes, Jagrati Jain

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Development of Phenotypic Drug Discovery Models for Tropical Parasitic Diseases, Surendra Kumar Jain

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Synthesis, Chemistry, Biological Evaluation And Structure-Activity Relationships Of Rac- And Chiral 6-Desmethyl-5Β –Hydroxy-D-Secoartemisinin And Analogs, Mohamed Elsideiq Jihan

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Molecular Characterization of the Opioid Receptors: Design, Development, and Preclinical Evaluation of Salvinorin A-Based Molecular Probes., Adam Keasling

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Synthesis and characterization of pH/temperature dual sensitive multiblock copolymer for drug delivery, Hyung Kyung Lee

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G-Quadruplexes As Molecular Targets For Transcriptional Control, Rhianna Kyelle Morgan

Predictors Of Medication Nonadherence In Children/Adolescents With Attention Deficit Hyperactivity Disorder (Adhd) In Mississippi Medicaid Program, Wahidullah Noori

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Patient Friendly Formulations Utilizing Hot Melt Extrusion Technology, Manjeet Bhagwan Pimparade

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Identification Of Stimulant Misuse And Malingering Of Symptoms Of Attention Deficit Hyperactivity Disorder, Sujith Ramachandran

Theses/Dissertations from 2016

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Saffron extract and its active constituents as preventative and/or treatment agents for prostate cancer using in vitro and in vivo models, FAISAL FAYIH ALBAQAMI

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Critical Quality Attributes of Topical Semi-solid Dosage Forms: Solvent Activity, Muralikrishnan Angamuthu

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Evaluation and enhancement of physical stability of amorphous solid dispersions, XIN FENG

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Payer Perspectives On Preemptive Pharmacogenetic Testing, Nicholas Keeling

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Novel approaches for ungual and trans-ungual delivery of drugs, Avadhesh Singh Kushwaha

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Targeting protein kinases to manage or prevent Alzheimer’s disease, Manal A. Nael

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Biological And Psychosocial Risk Factors Of Stroke In African Americans Enrolled In The Jackson Heart Study (Jhs), Sasikiran Nunna

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Hot-melt extrusion: A versatile pharmaceutical technology, Hemlata Patil

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Measuring And Understanding Health-Related Quality Of Life Among Adult Patients With Hemophilia, Ruchitbhai Mukesh Shah

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Biological and Chemical Investigation of Panamanian Plants for Potential Utility against Metabolic Syndrome, Yelkaira Vasquez

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Exploring new chemical entities from traditional medicine: Docking, synthesis and specific bioactivities, Chinni Yalamanchili

Theses/Dissertations from 2015

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Non-invasive drug delivery to the posterior segment of the eye: Development of formulation strategies and evaluation of ocular distribution and pharmacological activity, Goutham Reddy Adelli

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Effects of benzo[a]pyrene and CYP19a1b knockdown on zebrafish development, KHALID M. ALHARTHY

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Influence of hot melt extrusion processing parameters on the properties of a pharmaceutical formulation, Saad M. Alshahrani

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Design, synthesis, and biological evaluation of sigma receptors (σRS) ligands as potential pharmacotherapy for cancer and drug addiction, Walid Alsharif

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Versatility of hot-melt extrusion for dosage form design, Sultan Mohammad Alshehri

Solubility enhancement, mechanical properties and taste masking of poorly water soluble compounds by optimizing hot melt extrusion processing, Abdullah Saud Alshetaili

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Characterizing the Innate Immunity in the Hawaiian Coral Montipora capitata, Melinda S. Ansley

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Influence of novel techniques on solubility, mechanical properties and permeability via hot melt extrusion technology, Eman A. Ashour

Development Of The Medication Non-Adherence Scale (Mnas) And The Medication Non-Persistence Scale (Mnps), Amod Sudhir Athavale

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Design, Synthesis And Cannabinoid Receptor Activity Of Benzofuran Ligands, Eric William Bow

Ehtnobotanical- And Chemometric-Guided Investigation Of Phytolacca Americana L., Michael Chan

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Predictors Of Use Of Hydroxyurea And Its Impact On Clinical And Economic Outcomes Among Children With Sickle Cell Disease, Manasi Datar

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Primary Care Providers' Provision Of Therapeutic Lifestyle Change Counseling For Patients With Cardiovascular Risk, Tristen Jackson

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Quality of life and healthcare utilization and costs among adults with autism, Krutika Maulik Jariwala-Parikh

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Health Utility Assessment Among Caregivers of Individuals with Multiple Sclerosis, Namita Joshi

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Transdermal Iontophoretic Delivery Of Lipophilic Drugs, Abhishek Juluri

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Screening Of Natural Products For Their Effect On Kallikrein-Kinin System: Potential Implications In The Treatment Of Hereditary Angioedema, Hassan Abdu Madkhali

Effect Of Risk Evaluation And Mitigation Strategies (Rems) On Utilization Of Thiazolidinediones In A Medicaid Population, Clive Mario Mendonca

Novel Delivery Systems For Iron Replenishment, Naresh Modepalli

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Progress Toward The Total Synthesis Of The Natural Product Herbicide Ascaulitoxin Aglycone, Jeffery Brian Morgan

Endangered Plant Species For Potential Drug Leads And Anticancer Prototypes For Treatment Of Breast And Pancreatic Cancers, Joonseok Oh

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Protein-ligand interaction studies and identification of new drug-like hits as cannabinoid receptor modulators, Pankaj Pandey

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Lipid & surfactant based systems for improved delivery of poorly soluble APIs, Sri Satyasai Nagendra Babu Punyamurthula

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Youth With Type 1 Diabetes Mellitus: An Examination Of Adolescents’ Illness Perceptions And Associated Impact On Health-Related Quality Of Life, Zainab Shahpurwala

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Evaluation of inhibitors of histone deacetylases as potential neurotrophic agents, Surabhi Shukla

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Discovery of Alternative Artemisinin Binding Sites in Plasmodium falciparum ATPase-6, Shuneize Elizabeth Slater

Evaluation Of Novel Ligands For Opioid Receptors, Amer Hussien Tarawneh

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Impact Of Refill Synchronization On Medication Adherence For Chronic Diseases, Divya Verma

Theses/Dissertations from 2014

Evaluation Of Wild Yam (Dioscorea Villosa) As A Demethylating Agent And Its Anti Metastatic Activity In Human Breast Cancer Cells, Pranapda Aumsuwan

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Cranberry metabolites with urinary anti-adhesion activity, Christina M. Coleman

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Effects of nanosilver and silver nitrate exposure on fathead minnows (Pimephales promelas) and zebrafish (Danio rerio), Adam D. Hawkins